In mianyang, mianyang science and technology museum is established on the basis of the original old museum. For building China's red tourism base (families, work), the second half of 2005, mianyang municipal party committee, municipal government, rebuilding mianyang museum library as "rocket science and technology museum", then as "mianyang science and technology museum", Mr Zhou guangzhao, chairman of the China association for science and technology in mianyang science and technology museum wrote pavilion.

In September 2005, mianyang science and technology museum exhibition on display to start work.

On April 9, 2006, has built "China only wind tunnel, Asia's first space entertainment" and "China's third, the western conference Digistar3 digital screen cinema". Space and entertainment hole is mianyang, China aerodynamics research and development center to use their scientific research and development to mature technology applied to the success of entertainment project security, to fill the domestic blank.

In July 2006, with "rocket" as the theme of the exhibition display work in earnest.

After "5.12" earthquake in 2008, mianyang science and technology museum for earthquake damage detection and strengthening maintenance work, has been in a state of stagnation, to be built.

On June 28, 2009, mianyang municipal party committee secretary Wu Jingping hosting a party five 102th meeting, party committee of mianyang science and technology museum and post-earthquake recovery and reconstruction engineering related matters put forward clear requirements. In accordance with the decision of the municipal party committee, mianyang science and technology museum post-earthquake recovery and reconstruction project be completed in full before January 18, 2011.

On January 26, 2011, mianyang science and technology museum held the opening ceremony, officially opened.